Designing Inhibitors of Cytochrome c/Cardiolipin Peroxidase Complexes: Mitochondria-Targeted Imidazole-Substituted Fatty Acids

Mitochondria have emerged as the major regulatory platform responsible for coordination of numerous metabolic reactions as well as cell death processes, whereby the execution of intrinsic apoptosis includes the production of reactive oxygen species fueling oxidation of cardiolipin (CL) catalyzed by...

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Detalhes bibliográficos
Main Authors: Jiang, Jianfei, Bakan, Ahmet, Kapralov, Alexandr A., Silva, K. Ishara, Huang, Zhentai, Amoscato, Andrew A., Peterson, James, Garapati, Venkata Krishna, Saxena, Sunil, Bayir, Hülya, Atkinson, Jeffrey, Bahar, Ivet, Kagan, Valerian E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4216591/
https://ncbi.nlm.nih.gov/pubmed/24631490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2014.02.029
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