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Mitochondria-targeted disruptors and inhibitors of cytochrome c/cardiolipin peroxidase complexes: A new strategy in anti-apoptotic drug discovery

Critical role of mitochondria in programmed cell death leads to the design of mitochondriotropic agents as a strategy in regulating apoptosis. For anticancer therapy, stimulation of proapoptotic mitochondrial events in tumor cells and their suppression in surrounding normal cells represents a promis...

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Bibliografiske detaljer
Main Authors: Kagan, Valerian E., Bayir, Ayse, Bayir, Hulya, Stoyanovsky, Detcho, Borisenko, Grigory G., Tyurina, Yulia Y., Wipf, Peter, Atkinson, Jeffrey, Greenberger, Joel S., Chapkin, Robert S., Belikova, Natalia A.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2659540/
https://ncbi.nlm.nih.gov/pubmed/18979502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mnfr.200700402
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