Topography of tyrosine residues and their involvement in peroxidation of polyunsaturated cardiolipin in cytochrome c/cardiolipin peroxidase complexes

Formation of cytochrome c (cyt c)/cardiolipin (CL) peroxidase complex selective towards peroxidation of polyunsaturated CLs is a pre-requisite for mitochondrial membrane permeabilization. Tyrosine residues – via the generation of tyrosyl radicals (Tyr•) - are likely reactive intermediates of the per...

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Main Authors: Kapralov, Alexandr A., Yanamala, Naveena, Tyurina, Yulia Y., Castro, Laura, Arias, Alejandro Samhan, Vladimirov, Yuri A., Maeda, Akihiro, Weitz, Andrew A., Peterson, Jim, Mylnikov, Danila, Demicheli, Verónica, Tortora, Verónica, Klein-Seetharaman, Judith, Radi, Rafael, Kagan, Valerian E.
Format: Artigo
Jezik:Inglês
Izdano: 2011
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3321730/
https://ncbi.nlm.nih.gov/pubmed/21550335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2011.04.009
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