Peroxidase Activity and Structural Transitions of Cytochrome c Bound to Cardiolipin-Containing Membranes

During apoptosis, cytochrome c (cyt c) is released from intermembrane space of mitochondria into the cytosol where it triggers caspase-dependent machinery. We discovered that cyt c plays another critical role in early apoptosis as a cardiolipin (CL)-specific oxygenase to produce CL hydroperoxides re...

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Autori principali: Belikova, Natalia A., Vladimirov, Yury A., Osipov, Anatoly N., Kapralov, Alexandr A., Tyurin, Vladimir A., Potapovich, Maksim V., Basova, Liana V., Peterson, Jim, Kurnikov, Igor V., Kagan, Valerian E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2006
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527545/
https://ncbi.nlm.nih.gov/pubmed/16605268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi0525573
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