Structural Changes and Proapoptotic Peroxidase Activity of Cardiolipin-Bound Mitochondrial Cytochrome c

The cellular process of intrinsic apoptosis relies on the peroxidation of mitochondrial lipids as a critical molecular signal. Lipid peroxidation is connected to increases in mitochondrial reactive oxygen species, but there is also a required role for mitochondrial cytochrome c (cyt-c). In apoptotic...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Mandal, Abhishek, Hoop, Cody L., DeLucia, Maria, Kodali, Ravindra, Kagan, Valerian E., Ahn, Jinwoo, van der Wel, Patrick C.A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2015
Assuntos:
Membranes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4643272/
https://ncbi.nlm.nih.gov/pubmed/26536264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.09.016
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