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Implementation of the CRISPR-Cas9 system in fission yeast

Application of the CRISPR-Cas9 genome editing system in the model organism Schizosaccharomyces pombe has been hampered by the lack of constructs to express RNA of arbitrary sequence. Here we present expression constructs that use the promoter/leader RNA of RNA (rrk1) and a ribozyme to produce the ta...

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Bibliographic Details
Main Authors: Jacobs, Jake Z., Ciccaglione, Keith M., Tournier, Vincent, Zaratiegui, Mikel
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4215166/
https://ncbi.nlm.nih.gov/pubmed/25352017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6344
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