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CRISPR–Cas12a system in fission yeast for multiplex genomic editing and CRISPR interference

The CRISPR–Cas12a is a class II, type V clustered regularly interspaced short palindromic repeat (CRISPR) system with both RNase and DNase activity. Compared to the CRISPR–Cas9 system, it recognizes T-rich PAM sequences and has the advantage of multiplex genomic editing. Here, in fission yeast Schiz...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Zhao, Yu, Boeke, Jef D
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7261154/
https://ncbi.nlm.nih.gov/pubmed/32374858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa329
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