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Efficient Multiplex Genome Editing in Streptomyces via Engineered CRISPR-Cas12a Systems
Streptomyces strains produce a great number of valuable natural products. With the development of genome sequencing, a vast number of biosynthetic gene clusters with high potential for use in the discovery of valuable clinical drugs have been revealed. Therefore, emerging needs for tools to manipula...
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| Pubblicato in: | Front Bioeng Biotechnol |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Frontiers Media S.A.
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7338789/ https://ncbi.nlm.nih.gov/pubmed/32695773 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2020.00726 |
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