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Efficient Multiplex Genome Editing in Streptomyces via Engineered CRISPR-Cas12a Systems

Streptomyces strains produce a great number of valuable natural products. With the development of genome sequencing, a vast number of biosynthetic gene clusters with high potential for use in the discovery of valuable clinical drugs have been revealed. Therefore, emerging needs for tools to manipula...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Front Bioeng Biotechnol
Päätekijät: Zhang, Jun, Zhang, Dan, Zhu, Jie, Liu, Huayi, Liang, Shufang, Luo, Yunzi
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7338789/
https://ncbi.nlm.nih.gov/pubmed/32695773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2020.00726
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