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Efficient Multiplex Genome Editing in Streptomyces via Engineered CRISPR-Cas12a Systems

Streptomyces strains produce a great number of valuable natural products. With the development of genome sequencing, a vast number of biosynthetic gene clusters with high potential for use in the discovery of valuable clinical drugs have been revealed. Therefore, emerging needs for tools to manipula...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Front Bioeng Biotechnol
मुख्य लेखकों: Zhang, Jun, Zhang, Dan, Zhu, Jie, Liu, Huayi, Liang, Shufang, Luo, Yunzi
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Frontiers Media S.A. 2020
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7338789/
https://ncbi.nlm.nih.gov/pubmed/32695773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2020.00726
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