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CRISPR-Cas12a-Assisted Genome Editing in Amycolatopsis mediterranei

Amycolatopsis mediterranei U32 is an industrial producer of rifamycin SV, whose derivatives have long been the first-line antimycobacterial drugs. In order to perform genetic modification in this important industrial strain, a lot of efforts have been made in the past decades and a homologous recomb...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Front Bioeng Biotechnol
Hauptverfasser: Zhou, Yajuan, Liu, Xinqiang, Wu, Jiacheng, Zhao, Guoping, Wang, Jin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7332547/
https://ncbi.nlm.nih.gov/pubmed/32671053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2020.00698
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