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CRISPR-Cas12a-Assisted Genome Editing in Amycolatopsis mediterranei
Amycolatopsis mediterranei U32 is an industrial producer of rifamycin SV, whose derivatives have long been the first-line antimycobacterial drugs. In order to perform genetic modification in this important industrial strain, a lot of efforts have been made in the past decades and a homologous recomb...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2020-06-01
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| Colecção: | Frontiers in Bioengineering and Biotechnology |
| Assuntos: | |
| Acesso em linha: | https://www.frontiersin.org/article/10.3389/fbioe.2020.00698/full |
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