Multiplex genome editing of microorganisms using CRISPR-Cas

Microbial production of chemical compounds often requires highly engineered microbial cell factories. During the last years, CRISPR-Cas nucleases have been repurposed as powerful tools for genome editing. Here, we briefly review the most frequently used CRISPR-Cas tools and describe some of their ap...

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Bibliografiske detaljer
Udgivet i:FEMS Microbiol Lett
Main Authors: Adiego-Pérez, Belén, Randazzo, Paola, Daran, Jean Marc, Verwaal, René, Roubos, Johannes A, Daran-Lapujade, Pascale, van der Oost, John
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6522427/
https://ncbi.nlm.nih.gov/pubmed/31087001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/femsle/fnz086
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