Implementation of the CRISPR-Cas13a system in fission yeast and its repurposing for precise RNA editing

In contrast to genome editing, which introduces genetic changes at the DNA level, disrupting or editing gene transcripts provides a distinct approach to perturbing a genetic system, offering benefits complementary to classic genetic approaches. To develop a new toolset for manipulating RNA, we first...

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Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: Jing, Xinyun, Xie, Bingran, Chen, Longxian, Zhang, Niubing, Jiang, Yiyi, Qin, Hang, Wang, Hongbing, Hao, Pei, Yang, Sheng, Li, Xuan
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2018
Matèries:
Methods Online
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6125684/
https://ncbi.nlm.nih.gov/pubmed/29860393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky433
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