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Structure-Based Virtual Screening of the Nociceptin Receptor: Hybrid Docking and Shape-Based Approaches for Improved Hit Identification

[Image: see text] The antagonist-bound crystal structure of the nociceptin receptor (NOP), from the opioid receptor family, was recently reported along with those of the other opioid receptors bound to opioid antagonists. We recently reported the first homology model of the ‘active-state’ of the NOP...

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Bibliographic Details
Main Authors: Daga, Pankaj R., Polgar, Willma E., Zaveri, Nurulain T.
Format: Artigo
Language:Inglês
Published: American Chemical Society 2014
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210177/
https://ncbi.nlm.nih.gov/pubmed/25148595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ci500291a
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