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Structure-Based Virtual Screening of the Nociceptin Receptor: Hybrid Docking and Shape-Based Approaches for Improved Hit Identification

[Image: see text] The antagonist-bound crystal structure of the nociceptin receptor (NOP), from the opioid receptor family, was recently reported along with those of the other opioid receptors bound to opioid antagonists. We recently reported the first homology model of the ‘active-state’ of the NOP...

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Bibliografiset tiedot
Päätekijät: Daga, Pankaj R., Polgar, Willma E., Zaveri, Nurulain T.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Chemical Society 2014
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210177/
https://ncbi.nlm.nih.gov/pubmed/25148595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ci500291a
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