Structure-Based Virtual Screening of the Nociceptin Receptor: Hybrid Docking and Shape-Based Approaches for Improved Hit Identification

Lignende værker

• Probing ligand recognition of the opioid pan antagonist AT-076 at nociceptin, kappa, mu, and delta opioid receptors through structure-activity relationships
  af: Journigan, V. Blair, et al.
  Udgivet: (2017)
• Nociceptin/Orphanin FQ Receptor Activation Attenuates Antinociception Induced by Mixed Nociceptin/Orphanin FQ/μ-Opioid Receptor Agonists
  af: Khroyan, Taline V., et al.
  Udgivet: (2009)
• Discovery of the First Small-Molecule Opioid Pan Antagonist with Nanomolar Affinity at Mu, Delta, Kappa, and Nociceptin Opioid Receptors
  af: Zaveri, Nurulain T., et al.
  Udgivet: (2015)
• Homology Modeling and Molecular Dynamics Simulations of the Active State of the Nociceptin Receptor (NOP) Reveals New Insights Into Agonist Binding And Activation
  af: Daga, Pankaj R., et al.
  Udgivet: (2012)
• Differential In Vitro Pharmacological Profiles of Structurally Diverse Nociceptin Receptor Agonists in Activating G Protein and Beta-Arrestin Signaling at the Human Nociceptin Opioid Receptor
  af: Lu, James J., et al.
  Udgivet: (2021)