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Differential In Vitro Pharmacological Profiles of Structurally Diverse Nociceptin Receptor Agonists in Activating G Protein and Beta-Arrestin Signaling at the Human Nociceptin Opioid Receptor
Agonists at the nociceptin opioid peptide receptor (NOP) are under investigation as therapeutics for nonaddicting analgesia, opioid use disorder, Parkinson’s disease, and other indications. NOP full and partial agonists have both been of interest, particularly since NOP partial agonists show a reduc...
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| Publicado en: | Mol Pharmacol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The American Society for Pharmacology and Experimental Therapeutics
2021
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8256882/ https://ncbi.nlm.nih.gov/pubmed/33958480 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/molpharm.120.000076 |
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