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Disturbed vesicular trafficking of membrane proteins in prion disease
The pathogenic mechanism of prion diseases remains unknown. We recently reported that prion infection disturbs post-Golgi trafficking of certain types of membrane proteins to the cell surface, resulting in reduced surface expression of membrane proteins and abrogating the signal from the proteins. T...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Landes Bioscience
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4201611/ https://ncbi.nlm.nih.gov/pubmed/24335150 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.27381 |
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