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N-Terminal Regions of Prion Protein: Functions and Roles in Prion Diseases
The normal cellular isoform of prion protein, designated PrP(C), is constitutively converted to the abnormally folded, amyloidogenic isoform, PrP(Sc), in prion diseases, which include Creutzfeldt-Jakob disease in humans and scrapie and bovine spongiform encephalopathy in animals. PrP(C) is a membran...
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| Publicado no: | Int J Mol Sci |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7504422/ https://ncbi.nlm.nih.gov/pubmed/32872280 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21176233 |
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