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Disturbed vesicular trafficking of membrane proteins in prion disease

The pathogenic mechanism of prion diseases remains unknown. We recently reported that prion infection disturbs post-Golgi trafficking of certain types of membrane proteins to the cell surface, resulting in reduced surface expression of membrane proteins and abrogating the signal from the proteins. T...

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Detalhes bibliográficos
Main Authors: Uchiyama, Keiji, Miyata, Hironori, Sakaguchi, Suehiro
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201611/
https://ncbi.nlm.nih.gov/pubmed/24335150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.27381
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