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Synthesis of thioester peptides for the incorporation of thioamides into proteins by native chemical ligation()

Thioamides can be used as photoswitches, as reporters of local environment, as inhibitors of enzymes, and as fluorescence quenchers. We have recently demonstrated the incorporation of thioamides into polypeptides and proteins using native chemical ligation (NCL). In this protocol, we describe proced...

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Main Authors: Batjargal, Solongo, Huang, Yun, Wang, Yanxin J., Petersson, E. James
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4199922/
https://ncbi.nlm.nih.gov/pubmed/24408658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psc.2589
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