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Serine promoted synthesis of peptide thioester-precursor on solid support for native chemical ligation
Fmoc solid phase peptide synthesis of thioesters for the chemical synthesis of proteins via native chemical ligation is a challenge. We have developed a versatile approach for direct synthesis of peptide thioesters from a solid support utilizing Fmoc chemistry. Peptide thioester synthesis is perform...
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| Publicado en: | Chem Sci |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Royal Society of Chemistry
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5308276/ https://ncbi.nlm.nih.gov/pubmed/28451155 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6sc02162j |
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