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Native Chemical Ligation of Peptides and Proteins

For over 20 years, native chemical ligation (NCL) has played a pivotal role in enabling the total synthesis and semisynthesis of increasingly complex peptide and protein targets. Classical NCL proceeds by the chemoselective reaction of two unprotected polypeptide chains in near-neutral pH aqueous so...

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Detalhes bibliográficos
Publicado no:Curr Protoc Chem Biol
Main Authors: Cistrone, Philip A., Bird, Michael J., Flood, Dillon T., Silvestri, Anthony P., Hintzen, Jordi C. J., Thompson, Darren A., Dawson, Philip E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6384150/
https://ncbi.nlm.nih.gov/pubmed/30645048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpch.61
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