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Enhancing Native Chemical Ligation for Challenging Chemical Protein Syntheses

Native chemical ligation has enabled the chemical synthesis of proteins for a wide variety of applications (e.g., mirror-image proteins). However, inefficiencies of this chemoselective ligation in the context of large or otherwise challenging protein targets can limit the practical scope of chemical...

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Detalhes bibliográficos
Publicado no:Curr Opin Chem Biol
Main Authors: Giesler, Riley J., Erickson, Patrick W., Kay, Michael S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8106950/
https://ncbi.nlm.nih.gov/pubmed/32745915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2020.04.003
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