Chargement en cours...

Native Chemical Ligation of Thioamide-Containing Peptides: Development and Application to the Synthesis of Labeled α-Synuclein for Misfolding Studies

Thioamide modifications of the peptide backbone are used to perturb secondary structure, to inhibit proteolysis, as photoswitches, and as spectroscopic labels. Thus far, their incorporation has been confined to single peptides synthesized on solid phase. We have generated thioamides in C-terminal th...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Batjargal, Solongo, Wang, Yanxin J., Goldberg, Jacob M., Wissner, Rebecca F., Petersson, E. James
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3415603/
https://ncbi.nlm.nih.gov/pubmed/22468862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja2113245
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!