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Native Chemical Ligation of Thioamide-Containing Peptides: Development and Application to the Synthesis of Labeled α-Synuclein for Misfolding Studies

Thioamide modifications of the peptide backbone are used to perturb secondary structure, to inhibit proteolysis, as photoswitches, and as spectroscopic labels. Thus far, their incorporation has been confined to single peptides synthesized on solid phase. We have generated thioamides in C-terminal th...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Batjargal, Solongo, Wang, Yanxin J., Goldberg, Jacob M., Wissner, Rebecca F., Petersson, E. James
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3415603/
https://ncbi.nlm.nih.gov/pubmed/22468862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja2113245
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