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Chemoselective Modifications for the Traceless Ligation of Thioamide-Containing Peptides and Proteins
Thioamides are single-atom substitutions of canonical amide bonds, and have been proven to be versatile and minimally perturbing probes in protein folding studies. Previously, our group showed that thioamides can be incorporated into proteins by native chemical ligation (NCL) with Cys as a ligation...
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Publicado no: | Org Biomol Chem |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4927387/ https://ncbi.nlm.nih.gov/pubmed/27264841 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6ob01020b |
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