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Chemoselective Modifications for the Traceless Ligation of Thioamide-Containing Peptides and Proteins

Thioamides are single-atom substitutions of canonical amide bonds, and have been proven to be versatile and minimally perturbing probes in protein folding studies. Previously, our group showed that thioamides can be incorporated into proteins by native chemical ligation (NCL) with Cys as a ligation...

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Detalhes bibliográficos
Publicado no:Org Biomol Chem
Main Authors: Wang, Yanxin J., Szantai-Kis, D. Miklos, Petersson, E. James
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4927387/
https://ncbi.nlm.nih.gov/pubmed/27264841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6ob01020b
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