Role of casein kinase 1A1 in the biology and targeted therapy of del(5q) MDS

The Casein kinase 1A1 gene (CSNK1A1) is a putative tumor suppressor gene located in the common deleted region for del(5q) myelodysplastic syndrome (MDS). We generated a murine model with conditional inactivation of Csnk1a1 and found that Csnk1a1 haploinsufficiency induces hematopoietic stem cell exp...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Schneider, Rebekka K., Ademà, Vera, Heckl, Dirk, Järås, Marcus, Mallo, Mar, Lord, Allegra M., Chu, Lisa P., McConkey, Marie E., Kramann, Rafael, Mullally, Ann, Bejar, Rafael, Solé, Francesc, Ebert, Benjamin L.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4199102/
https://ncbi.nlm.nih.gov/pubmed/25242043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2014.08.001
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares