Gli1(+) mesenchymal stromal cells are a key driver of bone marrow fibrosis and an important cellular therapeutic target

Bone marrow fibrosis (BMF) develops in various hematological and non-hematological conditions and is a central pathological feature of myelofibrosis. Effective cell-targeted therapeutics are needed, but the cellular origin of BMF remains elusive. Here, we show using genetic fate tracing in two murin...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cell Stem Cell
Main Authors: Schneider, Rebekka K., Mullally, Ann, Dugourd, Aurelien, Peisker, Fabian, Hoogenboezem, Remco, Van Strien, Paulina M. H., Bindels, Eric M., Heckl, Dirk, Büsche, Guntram, Fleck, David, Müller-Newen, Gerhard, Wongboonsin, Janewit, Ventura Ferreira, Monica, Puelles, Victor G., Saez-Rodriguez, Julio, Ebert, Benjamin L., Humphreys, Benjamin D., Kramann, Rafael
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6485654/
https://ncbi.nlm.nih.gov/pubmed/28457748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2017.03.008
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados