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Perivascular Gli1+ progenitors are key contributors to injury-induced organ fibrosis

Mesenchymal stem cells (MSCs) reside in the perivascular niche of many organs, including kidney, lung, liver, and heart, although their roles in these tissues are poorly understood. Here, we demonstrate that Gli1 marks perivascular MSC-like cells that substantially contribute to organ fibrosis. In v...

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Podrobná bibliografie
Vydáno v:Cell Stem Cell
Hlavní autoři: Kramann, Rafael, Schneider, Rebekka K., DiRocco, Derek P., Machado, Flavia, Fleig, Susanne, Bondzie, Philip A., Henderson, Joel M., Ebert, Benjamin L., Humphreys, Benjamin D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4289444/
https://ncbi.nlm.nih.gov/pubmed/25465115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2014.11.004
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