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Understanding deregulated cellular and molecular dynamics in the haematopoietic stem cell niche to develop novel therapeutics for bone marrow fibrosis

Bone marrow fibrosis is the continuous replacement of blood‐forming cells in the bone marrow with excessive scar tissue, leading to failure of the body to produce blood cells and ultimately to death. Myofibroblasts are fibrosis‐driving cells and are well characterized in solid organ fibrosis, but th...

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Detalhes bibliográficos
Publicado no:J Pathol
Main Authors: Gleitz, Hélène FE, Kramann, Rafael, Schneider, Rebekka K
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5969225/
https://ncbi.nlm.nih.gov/pubmed/29570794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.5078
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