טוען...

MDM2, MDMX and p53 in oncogenesis and cancer therapy

The MDM2 and MDMX (also known as HDMX and MDM4) proteins are deregulated in many human cancers and exert their oncogenic activity predominantly by inhibiting the p53 tumour suppressor. However, the MDM proteins modulate and respond to many other signalling networks in which they are embedded. Recent...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Wade, Mark, Li, Yao-Cheng, Wahl, Geoffrey M.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2013
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4161369/
https://ncbi.nlm.nih.gov/pubmed/23303139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc3430
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!