Wild-type macrophages reverse disease in heme oxygenase 1-deficient mice

Loss-of-function mutation in the heme oxygenase 1 (Hmox1) gene causes a rare and lethal disease in children, characterized by severe anemia and intravascular hemolysis, with damage to endothelia and kidneys. Previously, we found that macrophages engaged in recycling of red cells were depleted from t...

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Bibliografiska uppgifter
Huvudupphovsmän: Kovtunovych, Gennadiy, Ghosh, Manik C., Ollivierre, Wade, Weitzel, R. Patrick, Eckhaus, Michael A., Tisdale, John F., Yachie, Akihiro, Rouault, Tracey A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society of Hematology 2014
Ämnen:
Red Cells, Iron, and Erythropoiesis
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4148774/
https://ncbi.nlm.nih.gov/pubmed/24963040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-02-554162
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