Infused wild-type macrophages reside and self-renew in the liver to rescue the hemolysis and anemia of Hmox1-deficient mice

Heme oxygenase 1 (HMOX1), the inducible enzyme that catabolizes the degradation of heme into biliverdin, iron, and carbon monoxide, plays an essential role in the clearance of senescent and damaged red blood cells, systemic iron homeostasis, erythropoiesis, vascular hemostasis, and oxidative and inf...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Kim, Ki Soon, Zhang, De-Liang, Kovtunovych, Gennadiy, Ghosh, Manik C., Ollivierre, Hayden, Eckhaus, Michael A., Rouault, Tracey A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2018
Assuntos:
Red Cells, Iron, and Erythropoiesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6199647/
https://ncbi.nlm.nih.gov/pubmed/30337301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018019737
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