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Infused wild-type macrophages reside and self-renew in the liver to rescue the hemolysis and anemia of Hmox1-deficient mice

Heme oxygenase 1 (HMOX1), the inducible enzyme that catabolizes the degradation of heme into biliverdin, iron, and carbon monoxide, plays an essential role in the clearance of senescent and damaged red blood cells, systemic iron homeostasis, erythropoiesis, vascular hemostasis, and oxidative and inf...

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Publicat a:Blood Adv
Autors principals: Kim, Ki Soon, Zhang, De-Liang, Kovtunovych, Gennadiy, Ghosh, Manik C., Ollivierre, Hayden, Eckhaus, Michael A., Rouault, Tracey A.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6199647/
https://ncbi.nlm.nih.gov/pubmed/30337301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018019737
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