Wild-type macrophages reverse disease in heme oxygenase 1-deficient mice

Loss-of-function mutation in the heme oxygenase 1 (Hmox1) gene causes a rare and lethal disease in children, characterized by severe anemia and intravascular hemolysis, with damage to endothelia and kidneys. Previously, we found that macrophages engaged in recycling of red cells were depleted from t...

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Detalhes bibliográficos
Main Authors: Kovtunovych, Gennadiy, Ghosh, Manik C., Ollivierre, Wade, Weitzel, R. Patrick, Eckhaus, Michael A., Tisdale, John F., Yachie, Akihiro, Rouault, Tracey A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2014
Assuntos:
Red Cells, Iron, and Erythropoiesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4148774/
https://ncbi.nlm.nih.gov/pubmed/24963040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-02-554162
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