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Conjugates of Cisplatin and Cyclooxygenase Inhibitors as Potent Antitumor Agents Overcoming Cisplatin Resistance()

Cyclooxygenase-2 (COX-2) is an enzyme involved in tumorigenesis, and inhibitors of the enzyme are increasingly used as adjuvant modulators in anticancer therapies due to their synergistic effects. The enzyme is also reported to cause resistance against antitumor agents, such as cisplatin. Here we re...

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書誌詳細
主要な著者: Neumann, Wilma, Crews, Brenda C., Marnett, Lawrence J., Hey-Hawkins, Evamarie
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136547/
https://ncbi.nlm.nih.gov/pubmed/24801194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201402074
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