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Conjugates of Cisplatin and Cyclooxygenase Inhibitors as Potent Antitumor Agents Overcoming Cisplatin Resistance()
Cyclooxygenase-2 (COX-2) is an enzyme involved in tumorigenesis, and inhibitors of the enzyme are increasingly used as adjuvant modulators in anticancer therapies due to their synergistic effects. The enzyme is also reported to cause resistance against antitumor agents, such as cisplatin. Here we re...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4136547/ https://ncbi.nlm.nih.gov/pubmed/24801194 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201402074 |
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