Scalable Preparation and Differential Pharmacologic and Toxicologic Profiles of Primaquine Enantiomers

Hematotoxicity in individuals genetically deficient in glucose-6-phosphate dehydrogenase (G6PD) activity is the major limitation of primaquine (PQ), the only antimalarial drug in clinical use for treatment of relapsing Plasmodium vivax malaria. PQ is currently clinically used in its racemic form. A...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Nanayakkara, N. P. Dhammika, Tekwani, Babu L., Herath, H. M. T. Bandara, Sahu, Rajnish, Gettayacamin, Montip, Tungtaeng, Anchalee, van Gessel, Yvonne, Baresel, Paul, Wickham, Kristina S., Bartlett, Marilyn S., Fronczek, Frank R., Melendez, Victor, Ohrt, Colin, Reichard, Gregory A., McChesney, James D., Rochford, Rosemary, Walker, Larry A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2014
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136050/
https://ncbi.nlm.nih.gov/pubmed/24913163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02674-13
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky