A Novel Ketolide, RBx 14255, with Activity against Multidrug-Resistant Streptococcus pneumoniae

We present here the novel ketolide RBx 14255, a semisynthetic macrolide derivative obtained by the derivatization of clarithromycin, for its in vitro and in vivo activities against sensitive and macrolide-resistant Streptococcus pneumoniae. RBx 14255 showed excellent in vitro activity against macrol...

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Bibliografiske detaljer
Main Authors: Raj, V. Samuel, Barman, Tarani Kanta, Kalia, Vandana, Purnapatre, Kedar, Dube, Smita, G., Ramkumar, Bhateja, Pragya, Mathur, Tarun, Chaira, Tridib, Upadhyay, Dilip J., Surase, Yogesh B., Venkataramanan, R., Chakrabarti, Anjan, Das, Biswajit, Bhatnagar, Pradip K.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2014
Fag:
Experimental Therapeutics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135985/
https://ncbi.nlm.nih.gov/pubmed/24550341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01589-13
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