DS86760016, a Leucyl-tRNA Synthetase Inhibitor with Activity against Pseudomonas aeruginosa

DS86760016 is a new leucyl-tRNA-synthetase inhibitor at the preclinical development stage. DS86760016 showed potent activity against extended-spectrum multidrug-resistant Pseudomonas aeruginosa isolated from clinical samples and in vitro biofilms. In a murine catheter-associated urinary tract infect...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Antimicrob Agents Chemother
Prif Awduron: Kumar, Manoj, Rao, Madhvi, Purnapatre, Kedar P., Barman, Tarani Kanta, Joshi, Vattan, Kashyap, Amuliya, Chaira, Tridib, Bambal, Ramesh B., Pandya, Manisha, Khodor, Souhaila Al, Upadhyay, Dilip J., Masuda, Nobuhisa
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2019
Pynciau:
Experimental Therapeutics
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6437482/
https://ncbi.nlm.nih.gov/pubmed/30670430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02122-18
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg