DS86760016, a Leucyl-tRNA Synthetase Inhibitor with Activity against Pseudomonas aeruginosa

DS86760016 is a new leucyl-tRNA-synthetase inhibitor at the preclinical development stage. DS86760016 showed potent activity against extended-spectrum multidrug-resistant Pseudomonas aeruginosa isolated from clinical samples and in vitro biofilms. In a murine catheter-associated urinary tract infect...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Kumar, Manoj, Rao, Madhvi, Purnapatre, Kedar P., Barman, Tarani Kanta, Joshi, Vattan, Kashyap, Amuliya, Chaira, Tridib, Bambal, Ramesh B., Pandya, Manisha, Khodor, Souhaila Al, Upadhyay, Dilip J., Masuda, Nobuhisa
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6437482/
https://ncbi.nlm.nih.gov/pubmed/30670430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02122-18
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