In Vitro and In Vivo Activities of DS86760016, a Novel Leucyl-tRNA Synthetase Inhibitor for Gram-Negative Pathogens

The emergence of multidrug-resistant (MDR) Gram-negative bacilli is a major concern in the treatment of nosocomial infections. Antibacterial agents with novel modes of action can be useful, as these pathogens have become resistant to almost all existing standard-of-care agents. GSK2251052, a leucyl-...

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Dades bibliogràfiques
Publicat a:Antimicrob Agents Chemother
Autors principals: Purnapatre, Kedar P., Rao, Madhvi, Pandya, Manisha, Khanna, Alka, Chaira, Tridib, Bambal, Ramesh, Upadhyay, Dilip J., Masuda, Nobuhisa
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2018
Matèries:
Experimental Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5913941/
https://ncbi.nlm.nih.gov/pubmed/29437618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01987-17
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