A Novel Ketolide, RBx 14255, with Activity against Multidrug-Resistant Streptococcus pneumoniae

We present here the novel ketolide RBx 14255, a semisynthetic macrolide derivative obtained by the derivatization of clarithromycin, for its in vitro and in vivo activities against sensitive and macrolide-resistant Streptococcus pneumoniae. RBx 14255 showed excellent in vitro activity against macrol...

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Main Authors: Raj, V. Samuel, Barman, Tarani Kanta, Kalia, Vandana, Purnapatre, Kedar, Dube, Smita, G., Ramkumar, Bhateja, Pragya, Mathur, Tarun, Chaira, Tridib, Upadhyay, Dilip J., Surase, Yogesh B., Venkataramanan, R., Chakrabarti, Anjan, Das, Biswajit, Bhatnagar, Pradip K.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2014
主題:
Experimental Therapeutics
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135985/
https://ncbi.nlm.nih.gov/pubmed/24550341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01589-13
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