A Novel Ketolide, RBx 14255, with Activity against Multidrug-Resistant Streptococcus pneumoniae

We present here the novel ketolide RBx 14255, a semisynthetic macrolide derivative obtained by the derivatization of clarithromycin, for its in vitro and in vivo activities against sensitive and macrolide-resistant Streptococcus pneumoniae. RBx 14255 showed excellent in vitro activity against macrol...

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Detalhes bibliográficos
Main Authors: Raj, V. Samuel, Barman, Tarani Kanta, Kalia, Vandana, Purnapatre, Kedar, Dube, Smita, G., Ramkumar, Bhateja, Pragya, Mathur, Tarun, Chaira, Tridib, Upadhyay, Dilip J., Surase, Yogesh B., Venkataramanan, R., Chakrabarti, Anjan, Das, Biswajit, Bhatnagar, Pradip K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135985/
https://ncbi.nlm.nih.gov/pubmed/24550341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01589-13
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