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In Vitro and In Vivo Activities of the Novel Ketolide RBx 14255 against Clostridium difficile
The MIC(90) of RBx 14255, a novel ketolide, against Clostridium difficile was 4 μg/ml (MIC range, 0.125 to 8 μg/ml), and this drug was found to be more potent than comparator drugs. An in vitro time-kill kinetics study of RBx 14255 showed time-dependent bacterial killing for C. difficile. Furthermor...
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Main Authors: | , , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Microbiology
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3486553/ https://ncbi.nlm.nih.gov/pubmed/22869573 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00015-12 |
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