A Novel Ketolide, RBx 14255, with Activity against Multidrug-Resistant Streptococcus pneumoniae

We present here the novel ketolide RBx 14255, a semisynthetic macrolide derivative obtained by the derivatization of clarithromycin, for its in vitro and in vivo activities against sensitive and macrolide-resistant Streptococcus pneumoniae. RBx 14255 showed excellent in vitro activity against macrol...

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Autors principals: Raj, V. Samuel, Barman, Tarani Kanta, Kalia, Vandana, Purnapatre, Kedar, Dube, Smita, G., Ramkumar, Bhateja, Pragya, Mathur, Tarun, Chaira, Tridib, Upadhyay, Dilip J., Surase, Yogesh B., Venkataramanan, R., Chakrabarti, Anjan, Das, Biswajit, Bhatnagar, Pradip K.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2014
Matèries:
Experimental Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135985/
https://ncbi.nlm.nih.gov/pubmed/24550341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01589-13
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