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RhoB Promotes γH2AX Dephosphorylation and DNA Double-Strand Break Repair
Unlike other Rho GTPases, RhoB is rapidly induced by DNA damage, and its expression level decreases during cancer progression. Because inefficient repair of DNA double-strand breaks (DSBs) can lead to cancer, we investigated whether camptothecin, an anticancer drug that produces DSBs, induces RhoB e...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4135599/ https://ncbi.nlm.nih.gov/pubmed/24912678 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01525-13 |
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