Transcription-dependent DNA double-strand breaks and human disease

Por Cristini, Agnese, Gromak, Natalia, Sordet, Olivier
Publicado no Mol Cell Oncol (2020)

RNA/DNA Hybrid Interactome Identifies DXH9 as a Molecular Player in Transcriptional Termination and R-Loop-Associated DNA Damage

Por Cristini, Agnese, Groh, Matthias, Kristiansen, Maiken S., Gromak, Natalia
Publicado no Cell Rep (2018)

DNA-PK triggers histone ubiquitination and signaling in response to DNA double-strand breaks produced during the repair of transcription-blocking topoisomerase I lesions

Por Cristini, Agnese, Park, Joon-Hyung, Capranico, Giovanni, Legube, Gaëlle, Favre, Gilles, Sordet, Olivier
Publicado no Nucleic Acids Res (2016)

Dynamic Effects of Topoisomerase I Inhibition on R-Loops and Short Transcripts at Active Promoters

Por Marinello, Jessica, Bertoncini, Stefania, Aloisi, Iris, Cristini, Agnese, Malagoli Tagliazucchi, Guidantonio, Forcato, Mattia, Sordet, Olivier, Capranico, Giovanni
Publicado no PLoS One (2016)

RhoB Promotes γH2AX Dephosphorylation and DNA Double-Strand Break Repair

Por Mamouni, Kenza, Cristini, Agnese, Guirouilh-Barbat, Josée, Monferran, Sylvie, Lemarié, Anthony, Faye, Jean-Charles, Lopez, Bernard S., Favre, Gilles, Sordet, Olivier
Publicado em 2014

PARP-1-dependent RND1 transcription induced by topoisomerase I cleavage complexes confers cellular resistance to camptothecin

Por Mouly, Laetitia, Mamouni, Kenza, Gence, Remi, Cristini, Agnese, Cherier, Julia, Castinel, Adrien, Legrand, Morgane, Favre, Gilles, Sordet, Olivier, Monferran, Sylvie
Publicado no Cell Death Dis (2018)

N6-methyladenosine regulates the stability of RNA:DNA hybrids in human cells

Por Abakir, Abdulkadir, Giles, Tom C., Cristini, Agnese, Foster, Jeremy M., Dai, Nan, Starczak, Marta, Rubio-Roldan, Alejandro, Li, Miaomiao, Eleftheriou, Maria, Crutchley, James, Flatt, Luke, Young, Lorraine, Gaffney, Daniel J., Denning, Chris, Dalhus, Bjørn, Emes, Richard D., Gackowski, Daniel, Corrêa, Ivan R., Garcia-Perez, Jose L., Klungland, Arne, Gromak, Natalia, Ruzov, Alexey
Publicado no Nat Genet (2019)