Role of the double-strand break repair pathway in the maintenance of genomic stability

DNA double-strand breaks (DSBs) are highly lethal lesions that jeopardize genome integrity. However, DSBs are also used to generate diversity during the physiological processes of meiosis or establishment of the immune repertoire. Therefore, DSB repair must be tightly controlled. Two main strategies...

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Bibliografiska uppgifter
I publikationen:Mol Cell Oncol
Huvudupphovsmän: Le Guen, Tangui, Ragu, Sandrine, Guirouilh-Barbat, Josée, Lopez, Bernard S
Materialtyp: Artigo
Språk:Inglês
Publicerad: Taylor & Francis 2014
Ämnen:
Review
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905226/
https://ncbi.nlm.nih.gov/pubmed/27308383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/23723548.2014.968020
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