Cargando...
Biochemical assays for the discovery of TDP1 inhibitors
Drug screening against novel targets is warranted to generate biochemical probes and new therapeutic drug leads. Tyrosyl-DNA-phosphodiesterases 1 and 2 (TDP1 and TDP2) are two DNA repair enzymes that have yet to be successfully targeted. TDP1 repairs topoisomerase I-, alkylation-, and chain terminat...
Gardado en:
| Main Authors: | , , , , , , , , , , , , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2014
|
| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4126877/ https://ncbi.nlm.nih.gov/pubmed/25024006 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-13-0952 |
| Tags: |
Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|