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Translational Control by Heme-Regulated eIF2α Kinase during Erythropoiesis

PURPOSE OF REVIEW: This review will provide an overview of the translational regulation of globin mRNAs and integrated stress response during erythropoiesis by heme-regulated eIF2α kinase (HRI). HRI is an intracellular heme sensor that coordinates heme and globin synthesis in erythropoiesis by inhib...

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Autor principal: Chen, Jane-Jane
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4124034/
https://ncbi.nlm.nih.gov/pubmed/24714526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MOH.0000000000000030
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