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Translational Control by Heme-Regulated eIF2α Kinase during Erythropoiesis
PURPOSE OF REVIEW: This review will provide an overview of the translational regulation of globin mRNAs and integrated stress response during erythropoiesis by heme-regulated eIF2α kinase (HRI). HRI is an intracellular heme sensor that coordinates heme and globin synthesis in erythropoiesis by inhib...
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| Auteur principal: | |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4124034/ https://ncbi.nlm.nih.gov/pubmed/24714526 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MOH.0000000000000030 |
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