Cargando...

Synthesis and Biological Evaluation of Phosphonate Derivatives as Autotaxin (ATX) Inhibitors

Autotaxin (ATX) is an autocrine motility factor that promotes cancer cell invasion, cell migration and angiogenesis. ATX, originally discovered as a nucleotide phosphodiesterase, is known now to be responsible for the lysophospholipid-preferring phospholipase D activity in plasma. As such, it cataly...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Cui, Peng, Tomsig, Jose L., McCalmont, William F., Lee, Sangderk, Becker, Christopher J., Lynch, Kevin R., Macdonald, Timothy L.
Formato: Artigo
Idioma:Inglês
Publicado: 2007
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4116752/
https://ncbi.nlm.nih.gov/pubmed/17257836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2006.12.114
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!