A New Enzyme Immunoassay for the Quantitative Determination of Classical Autotaxins (ATXα, ATXβ, and ATXγ) and Novel Autotaxins (ATXδ and ATXε)

BACKGROUND: Autotaxin (ATX) is a secreted enzyme that converts lysophosphatidylcholine to lysophosphatidic acid, a potent bioactive lipid mediator, through its lysophospholipase D activity. Although five alternative splicing isoforms of ATX have been identified as ATXα, ATXβ, ATXγ, ATXδ, and ATXε an...

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Veröffentlicht in:PLoS One
Hauptverfasser: Tokuhara, Yasunori, Kurano, Makoto, Shimamoto, Satoshi, Igarashi, Koji, Nojiri, Takahiro, Kobayashi, Tamaki, Masuda, Akiko, Ikeda, Hitoshi, Nagamatsu, Takeshi, Fujii, Tomoyuki, Aoki, Junken, Yatomi, Yutaka
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4471343/
https://ncbi.nlm.nih.gov/pubmed/26083365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0130074
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