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Dendrimer Conjugate of [4-(Tetradecanoylamino)benzyl]phosphonic Acid (S32826) as an Autotaxin Inhibitor

[Image: see text] Autotaxin is an extracellular phospholipase D that catalyzes the hydrolysis of lysophosphatidyl choline (LPC) to bioactive lipid lysophosphatidic acid (LPA). LPA has been implicated in many pathological processes relevant to cancer, including cell migration and invasion, proliferat...

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Détails bibliographiques
Auteurs principaux: Fisher, Natalie, Hilton-Bolt, Timothy, Edwards, Michael G., Haxton, Katherine J., McKenzie, Michael, Allin, Steven M., Richardson, Alan
Format: Artigo
Langue:Inglês
Publié: American Chemical Society 2013
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4027627/
https://ncbi.nlm.nih.gov/pubmed/24900771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml4003106
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