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Dendrimer Conjugate of [4-(Tetradecanoylamino)benzyl]phosphonic Acid (S32826) as an Autotaxin Inhibitor

[Image: see text] Autotaxin is an extracellular phospholipase D that catalyzes the hydrolysis of lysophosphatidyl choline (LPC) to bioactive lipid lysophosphatidic acid (LPA). LPA has been implicated in many pathological processes relevant to cancer, including cell migration and invasion, proliferat...

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Hlavní autoři: Fisher, Natalie, Hilton-Bolt, Timothy, Edwards, Michael G., Haxton, Katherine J., McKenzie, Michael, Allin, Steven M., Richardson, Alan
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2013
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4027627/
https://ncbi.nlm.nih.gov/pubmed/24900771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml4003106
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