Dendrimer Conjugate of [4-(Tetradecanoylamino)benzyl]phosphonic Acid (S32826) as an Autotaxin Inhibitor

[Image: see text] Autotaxin is an extracellular phospholipase D that catalyzes the hydrolysis of lysophosphatidyl choline (LPC) to bioactive lipid lysophosphatidic acid (LPA). LPA has been implicated in many pathological processes relevant to cancer, including cell migration and invasion, proliferat...

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Detalhes bibliográficos
Main Authors: Fisher, Natalie, Hilton-Bolt, Timothy, Edwards, Michael G., Haxton, Katherine J., McKenzie, Michael, Allin, Steven M., Richardson, Alan
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2013
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4027627/
https://ncbi.nlm.nih.gov/pubmed/24900771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml4003106
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